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| Article Title: | |||||||||
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A preliminary study on the relaxant effect of the crude extract and fractions of the bark of Chrysophyllum cainito L. in isolated rat thoracic aorta.
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| Author(s) | |||||||||
Quentela, Albert
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Apostol, Jovencio
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Ysrael, Mafel C.
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Wadsworth, Roger M.
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| Publication Title : | Acta Manilana | ||
| 2001,vol./issue 49 | |||
| Pagination/Coll : | 49-54. graphs, table. 4 refs. | ||
| CallNum : | STII Fil Q181.A81 | ||
| Subjects | Pharmacology | ||
| Methanol--Extraction | |||
| Chrysophyllum cainito--Bark--Methanol content | |||
| Medicinal plants | |||
| Caimito | |||
| Abstracts: | The crude methanol extract of the bark of C. cainito was partitioned using solvents of increasing polarities, namely hexane, dichloromethane, butanol and water. Isolated thoracic aortic rings with intact endothelium from male Sprague-Dawley rats were used to screen the vasorelaxant activity of the crude extract and its fractions. Results showed that the methanol extract and its fractions caused concentration-dependent relaxation of the vascular smooth muscle. Methanol extract and water fraction exhibited the most profound effects. | |||
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